Shenzhen Liandaqi Precision Ceramic Co., Ltd.

Shenzhen Liandaqi Precision Ceramic Co., Ltd.

Analysis of Core Technology of Medical Micro-Net Aerosolization Chip - How to Achieve Precise Aerosolization and Efficient Drug Delivery within 2–5μm

2026 04/14

Introduction

In the nebulization treatment of respiratory diseases, particle size is a core indicator determining the efficiency of drug delivery - only aerosol particles ranging from 2 to 5μm can penetrate deep into the pulmonary alveoli, achieving efficient absorption. As the "heart component" of medical nebulizers, the technical level of micro-mesh nebulizing chips directly determines the nebulization effect and treatment experience. Shenzhen Liandaqi Precision Ceramics Co., Ltd. (hereinafter referred to as "Liandaqi") relies on the precision manufacturing advantages of the HuiKe Industrial Park in Shiyan, Shenzhen, and with piezoelectric ceramic drive + micro-pore precision machining as its core, has developed nebulizing chip products that meet medical-grade requirements, providing stable and reliable core support for medical nebulizers.

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Core technical principle: Synergistic breakthrough in piezoelectric actuation and microporous screen atomization

The core logic of the medical micro-net atomizing chip lies in the efficient conversion of electrical energy into mechanical energy, and then into atomizing energy. Through two major technological breakthroughs, Liandaqi has achieved precise atomization:

1. Piezoelectric Ceramic Drive Technology: Utilizing self-developed high-purity piezoelectric ceramic materials, it converts electrical energy into high-frequency mechanical vibrations ranging from 100 to 200 kHz. The vibration response is fast and the energy loss is low, ensuring stable and controllable atomization process. The product's resonant frequency is precisely controlled at 103–108±3 kHz, adapting to different medical nebulizer drive requirements and providing a stable power source for microporous sieve atomization.

2. Micro-hole Precision Machining Process: Utilizing high-precision laser drilling technology, we create uniformly distributed micron-sized micro-holes on the surface of steel sheets. The hole diameter is strictly controlled at 3–4μm, with a hole count ranging from 1200 to 2000. The hole diameter error is maintained within ±0.05μm. Unlike traditional etching processes, which often result in irregular hole shapes and uneven distribution, Lian Daqi's micro-hole process prevents the formation of large droplets from the outset, ensuring uniformity of atomized particles.

Core performance indicators: Defining medical-grade quality through data

The LianDaQi medical micro-net atomizing chip benchmarks international standards with rigorous data, and its core indicators reach the industry-leading level:

performance metrics

measured data

clinical significance

Proportion of atomized particles1–5μm)

≥70%

Over 70% of the particles can directly reach the pulmonary alveoli, significantly enhancing the drug deposition rate

median particle sizeD50)

3±25%

Accurately matching the treatment needs of the lower respiratory tract, suitable for conditions such as asthma and COPD

atomization rate

≥0.3mL/min

Ensure treatment efficiency and shorten nebulization time

Recommended Power

1.5W

Low-power operation, compatible with portable nebulizers

Drug residue rate

0.8mL

Reduce liquid medicine waste and improve drug utilization rate

 

The achievement of these indicators stems from Lian Daqi's technical polishing across the entire chain of material formulation, structural design, and processing technology, ensuring that every atomizing plate can stably deliver medical-grade atomization effects.

Clinical value and application scenarios: Precisely adapting to all medical scenarios

1. Treatment of lower respiratory tract diseases: 3–4μm atomized particles can penetrate deep into the pulmonary alveoli, making them suitable for conditions such as asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis. The drug deposition rate is increased by over 30% compared to traditional nebulizers, reducing gastrointestinal irritation and making it particularly suitable for children and elderly patients.

2. Upper respiratory tract care: Particles of 5–7μm can cover the oral and pharyngeal mucosa, suitable for oral sprays and nebulized treatment for pharyngeal inflammation, meeting the daily care needs in clinics and at home.

3. Special drug delivery: The no-heating atomization mode avoids the destruction of the activity of biologics, making it suitable for the atomization of antibiotics and protein drugs, thereby broadening the application boundaries of medical atomization.

Conclusion

The core technology of medical micro-net atomizing tablets lies in "precision" and "stability" - every breakthrough in every link, from piezoelectric materials to micro-pore processing, directly affects clinical outcomes. Lian Daqi, relying on the precision manufacturing foundation of the Huike Industrial Park in Shiyan, Shenzhen, takes independent research and process innovation as its core, creating medical atomizing tablet products that not only meet the stringent safety standards of medical atomizers but also achieve efficient drug delivery, providing reliable core component support for the atomization treatment of respiratory diseases. In the future, Lian Daqi will continue to deeply explore micro-pore atomization technology, promote the localization and upgrading of medical atomizing tablets, and contribute to the implementation of the Healthy China 2030 strategy.